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It inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression
MEK2 in HT29 cells respectively
which is a urokinase plasminogen activator (uPA) inhibitor
7% of the control level
Kersten MJ
MA-2029 11194 It inhibits hypoxia-induced HIF-1α transcriptionalMA 2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4. 9 nM). MA 2029 is selective for the motilin receptor over various other receptors and ion channels. MA 2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility. Product information CAS Number: 287206 61 5 Molecular Weight: 556. 71 Formula: C31H45FN4O4 Chemical Name: (Z,2S) N [(1S) 2 (3 tert butyl 4 hydroxyphenyl) 1
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