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BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid 1S xenograft by IP injection

SKU: 95049401656

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Description

1S xenograft by IP injection at 50 mg/kg (5 days a week)

1203494-49-8

1 μM canertinib inhibits ErbB1-3 receptor phosphorylation with a concomitant decrease of Akt-

an EC50 value comparable to that of our previously described benzoxoloazepinolone

507: a subnanomolar human beta 3 adrenergic receptor agonist

BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid 1S xenograft by IP injectionBI 9564, CAS No. 1883429 22 8, is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14. 1 and 239 nM; IC50s = 75 nM and 3. 4 M, respectively). BI 9564 is useful in further exploring BRD9 bromodomain biology in both in vitro and in vivo settings. Selective inhibitors of bromodomain containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases. Product information CAS

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