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Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models
CAS Number: 885325-71-3
orally bioavailable Sortilin inhibitor
Solubility: DMSO : 100 mg/mL (309
InChiKey: CIORWBWIBBPXCG-UHFFFAOYSA-N
MK-4074 198ithionol Intracellular Released Payload Influences PotencyMK 4074 is a liver specific inhibitor of acetyl CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM. Product information CAS Number: 1039758 22 9 Molecular Weight: 565. 62 Formula: C33H31N3O6 Chemical Name: 5 [1' (1 cyclopropyl 4 methoxy 3 methyl 1H indole 6 carbonyl) 4 oxo 3,4 dihydrospiro[1 benzopyran 2,4' piperidin] 6 yl]pyridine 3 carboxylic acid Smiles:
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