MG-277 164015 CCN1C2C(=CN=CC=2C(=O)N2CC[C@H](N)C2)N=C1C1=NON=C1N

CCN1C2C(=CN=CC=2C(=O)N2CC[C@H](N)C2)N=C1C1=NON=C1N

aeruginosa infections was caused by an exuberant neutrophil response stimulated by 3-O-C12-HSL-induced IL-8

cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist

γ-Terpinene (γ-TPN

It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase-1

MG-277 164015 CCN1C2C(=CN=CC=2C(=O)N2CC[C@H](N)C2)N=C1C1=NON=C1NMG 277, a molecular glue degrader, effectively induces degradation of a translation termination factor, GSPT1, with a DC50 of 1. 3 nM. MG 277 potently inhibits tumor cell growth in a p53 independent manner, with IC50s of 3. 5 nM for RS4; 11 cells and 3. 4 nM for p53 mutant RS4; 11 IRMI 2 cells, respectively. Anticancer activity. Product information CAS Number: 2411085 89 5 Molecular Weight: 774. 71 Formula: C41H42Cl2FN5O5 Chemical Name: (3'R,4'S,5'R)