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PP121 is a multitargeted dual receptor tyrosine kinases inhibitor
Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5
Mathieson T
AMPK activator 1 is an AMPK activator extracted from patent WO2013116491A1
3-1(4)2(5)6/h8H
Losartan Carboxaldehyde 6681509 PP121 is a multitargeted dualLosartan is an inhibitor of endothelial cyclooxygenase (COX) 2. COX 2 produces prostaglandins that inhibit apoptosis and stimulate angiogenesis and invasiveness, and thus selective COX 2 inhibitors can reduce prostaglandin synthesis and restore apoptosis. In vitro: Losartan is an intermediate aldehyde metabolite of losartan, the angiotensin II type 1 receptor antagonist. Losartan could not block angiotensin receptors, but inhibit the expression of
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