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ML314 has no significant response in a Ca2+ mobilization assay and is thus a biased agonist that activates the β-arrestin pathway rather than the traditional Gq coupled pathway
The growth of cells is suppressed in a time- and dose-dependent manner
also known as GS-6207
5-trifluorophenyl)methyl]carbamate
UPF-1069 induces apoptosis
Reveromycin A annitol ML314 has no significant responseReveromycin A, a benzoquinoid antibiotic isolated from the genus Streptomyces, is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity. Product information CAS Number: 134615 37 5 Molecular Weight: 660. 79 Formula: C36H52O11 Chemical Name: (2E, 4S, 5S, 6E, 8E)
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