KN-93 Hydrochloride Catalog No.:M9578-10 Smiles: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO

Smiles: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO

the resulting complex becomes activated and binds to specific sites on DNA

Krumbach R

which induced dose- and time-dependent cytotoxicity in a variety of multiple myeloma (MM) cell lines

tumor growth inhibition increases with increased exposure of the compound and that tumor regressions could only be achieved when the compound exposure consistently exceeded 90% of c-MET inhibition

KN-93 Hydrochloride Catalog No.:M9578-10 Smiles: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)COKN 93 is an inhibitor of Ca2+ calmodulin dependent protein kinase II (CaMK II). It inhibits fibroblast CaMK II activity and cell growth in a dose dependent manner, reversibly arrests cells in G1 and induces apoptosis. Product information CAS Number: 1956426 56 4 Molecular Weight: 537. 50 Formula: C26H30Cl2N2O4S Chemical Name: N [2 ({[(2E) 3 (4 chlorophenyl)prop 2 en 1 yl](methyl)amino}methyl)phenyl] N (2 hydroxyethyl) 4 methoxybenzene 1 sulfonamide