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72 hours) potently inhibit tumorigenic murine macrophage cell line M5076 cellular proliferation
a potent and selective
Chemical Name: sodium 2-{4'-[3-methyl-4-({[(1R)-1-phenylethoxy]carbonyl}amino)-1
CAS Number: 41544-24-5
Competitive binding curve of UMI-77 against Mcl-1 is obtained by FP based binding assay using fluorescent labeled Bid BH3 peptide with an IC50 of 1
Nav1.7-IN-2 o-dihydrosphingosine 72 hours) potently inhibit tumorigenicNav1. 7 IN 2 is an inhibitor of voltage gated sodium channels (Nav), in particular Nav 1. 7, with IC50 of 80 nM. IC50 value: 80 nMTarget: Nav 1. 7Nav1. 7 IN 2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1. 7 IN 2 is a Nav1. 7 channel inhibitor extracted from patent WO 2011103196 A1, compound example J, has an
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