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Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells
BLU-9931 shows remarkable antitumor activity in mice bearing an HCC tumor xenograft that overexpresses FGF19 due to amplification as well as a liver tumor xenograft that overexpresses FGF19 mRNA but lacks FGF19 amplification
InChiKey: FWCVZAQENIZVMY-UHFFFAOYSA-N
but not H3K56ac as revealed by western blot analysis
477(7365):477-81
Dorzolamide Size:2mg solid Small Molecules Enhance CRISPR GenomeDorzolamide is a carbonic anhydrase inhibitor. It is an anti glaucoma agent, and acts by decreasing the production of aqueous humour. It is administered as a topical ophthalmic in the form of a 2% solution. Product information CAS Number: 120279 96 1 Molecular Weight: 324. 44 Formula: C10H16N2O4S3 Synonym: UNII 9JDX055TW1 UNII9JDX055TW1 UNII 9JDX055TW1 Chemical Name: (4S, 6S) 4 (ethylamino) 6 methyl 5, 6 dihydro 4H thieno[2, 3 b]thiopyran 2
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