LP-211 n 6-O-β-D-glucoside The extent of retinal neovascularization

The extent of retinal neovascularization in a mouse OIR model is reduced by approximately 60% after treatment with TBB (6 days at 60 mg/kg per day)

InChi: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7

Chemical Name: 1-[(9Z)-octadec-9-enoyloxy]-2

Chemical Name: 5-[(Z)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1

Consistent with its antinociceptive effects in the hot-plate assay

LP-211 n 6-O-β-D-glucoside The extent of retinal neovascularizationLP 211 is a selective and bloodbrain barrier penetrant 5 HT7 receptor agonist, with a Ki of 0. 58 nM, with high selectivity over 5 HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). Product information CAS Number: 1052147 86 0 Molecular Weight: 466. 62 Formula: C30H34N4O Chemical Name: 6 (4 {[1,1' biphenyl] 2 yl}piperazin 1 yl) N [(4 cyanophenyl)methyl]hexanamide Smiles: N#CC1C=CC(CNC(=O)CCCCCN2CCN(CC2)C2=CC=CC=C2C2C=CC=CC=2)=CC=1 InChiKey: